KAISO Antibody, mAb, Rabbit

Description

Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5-CGCG-3 and also binds to the non-methylated consensus sequence 5-CTGCNA-3 also known as the consensus kaiso binding site KBS . Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters.