GENERAL CATALOGUE
KB02-JQ1
HY-129917 · 1 mg
MedChemExpress · Cat: HY-129917
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medchemexpress.com/kb02-jq1.htmlCatalog No: HY-129917
CAS No: 2384184-44-3
Category: Epigenetics
Pack Size: 1 mg
Brand: MedChemExpress
Description
KB02-JQ1 is a highly selective and PROTAC-based BRD4 degrader molecular glue , but does not degrade BRD2 or BRD3. KB02-JQ1 promotes BRD4 degradation by covalently modifying DCAF16 E3 ligase and can improve the durability of protein degradation in biological systems. JQ1 binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-JQ1.
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