

HY-129610 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-129610
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/kb02-slf.htmlDescription
KB02-SLF is a PROTAC-based nuclear FKBP12 degrader molecular glue . KB02-SLF promotes nuclear FKBP12 degradation by covalently modifying DCAF16 E3 ligase and can improve the durability of protein degradation in biological systems. SLF binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02-SLF.