KD-Validated ABCD1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated ABCD1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:ABCD1; ATP Binding Cassette Subfamily D Member 1; ALDP; AMN; ALD; ATP-Binding Cassette, Sub-Family D (ALD), Member 1; ATP-Binding Cassette Sub-Family D Member 1; Adrenoleukodystrophy Protein; Adrenoleukodystrophy; ADRENOLEUKODYSTROPHY; EC 3.1.2.-; EC 7.6.2.-; ABC42 Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008] Research Area: Tags & Cell Markers,Signal Transduction,Cancer,Metabolism