KD-Validated Acetyl-CoA Carboxylase Alpha Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Acetyl-CoA Carboxylase Alpha Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:ACACA; Acetyl-CoA Carboxylase Alpha; ACC1; ACCA; Acetyl-Coenzyme A Carboxylase Alpha; Acetyl-CoA Carboxylase 1; ACC-Alpha; HACC1; ACAC; ACACalpha; ACCalpha; Acac1; ACC; EC 6.4.1.2; ACACALPHA; ACC-ALPHA; ACCALPHA; ACACAD; ACAC1 Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Research Area: Cardiovascular,Signal Transduction,Cancer,Metabolism