KD-Validated Actin Like 6A Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Actin Like 6A Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:ACTL6A; Actin Like 6A; BAF53A; INO80K; BRG1-Associated Factor 53A; INO80 Complex Subunit K; SMARCN1; 53 KDa BRG1-Associated Factor A; Actin-Related Protein Baf53a; BAF Complex 53 KDa Subunit; Actin-Related Protein; Actin-Like Protein 6A; ArpNbeta; ACTL6; BAF53; Arp4; HArpN Beta; ARPN-BETA; Baf53a; Actl6; ARP4 Background: This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008] Research Area: Signal Transduction