KD-Validated AIMP1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated AIMP1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:AIMP1; Aminoacyl TRNA Synthetase Complex Interacting Multifunctional Protein 1; EMAPII; SCYE1; P43; Small Inducible Cytokine Subfamily E, Member 1 (Endothelial Monocyte-Activating); Aminoacyl TRNA Synthase Complex-Interacting Multifunctional Protein 1; Multisynthetase Complex Auxiliary Component P43; Multisynthase Complex Auxiliary Component P43; ARS-Interacting Multifunctional Protein 1; EMAP-2; EMAP2; Endothelial-Monocyte Activating Polypeptide II; Endothelial Monocyte-Activating Polypeptide; EMAP II; HLD3 Background: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008] Research Area: Cell Biology,Cardiovascular,Immunology,Tags & Cell Markers,Epigenetics and Nuclear Signaling,Cancer