KD-Validated ALPL Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated ALPL Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Alkaline Phosphatase, Biomineralization Associated; TNSALP; TNALP; TNAP; Alkaline Phosphatase, Tissue-Nonspecific Isozyme; Alkaline Phosphatase Liver/Bone/Kidney Isozyme; Tissue Non-Specific Alkaline Phosphatase; Alkaline Phosphatase, Liver/Bone/Kidney; Phosphocreatine Phosphatase; Phosphoamidase; EC 3.1.3.1; AP-TNAP; TNS-ALP; HOPS; Liver/Bone/Kidney-Type Alkaline Phosphatase; Tissue-Nonspecific ALP; EC 3.9.1.1; APTNAP; HPPA; HPPC; HPPI; HPPO Background: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015] Research Area: Cell Biology,Tags & Cell Markers,Cancer