KD-Validated Amyloid Beta Precursor Like Protein 2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Amyloid Beta Precursor Like Protein 2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:APLP2; Amyloid Beta Precursor Like Protein 2; APPH 2; Amyloid Beta (A4) Precursor-Like Protein 2; APPL2; Sperm Membrane Protein YWK-II; CDEI Box-Binding Protein; APLP-2; CDEBP; Amyloid Precursor Protein Homolog HSD-2; Testicular Tissue Protein Li 23; Amyloid Protein Homolog; Amyloid-Like Protein 2 Background: This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] Research Area: Neuroscience