KD-Validated AP3M1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated AP3M1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:AP3M1; Adaptor Related Protein Complex 3 Subunit Mu 1; Adaptor Related Protein Complex 3 Mu 1 Subunit; AP-3 Complex Subunit Mu-1; Mu-Adaptin 3A; Mu3A-Adaptin; Adapter-Related Protein Complex 3 Mu-1 Subunit; Adaptor-Related Protein Complex 3 Subunit Mu-1; Clathrin Adaptor Complex AP3, Mu-3A Subunit; AP-3 Adapter Complex Mu3A Subunit; AP-3 Adaptor Complex Mu3A Subunit Background: The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016] Research Area: Signal Transduction