KD-Validated Arginase 2 Rabbit Polyclonal Antibody

Description

EnkiLife offers the KD-Validated Arginase 2 Rabbit Polyclonal Antibody. This antibody reacts with Human and is suitable for WB,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; IHC-P 1:50-1:100 Alternative Names of Immunogen:ARG2; Arginase 2; Arginase-2, Mitochondrial; Kidney-Type Arginase; Non-Hepatic Arginase; Arginase, Type II; Type II Arginase; Arginase II; EC 3.5.3.1; L-Arginine Amidinohydrolase; L-Arginine Ureahydrolase; Nonhepatic Arginase; Kidney Arginase; EC 3.5.3 Background: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008] Research Area: Signal Transduction,Metabolism