KD-Validated ARHGDIA Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated ARHGDIA Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:ARHGDIA; Rho GDP Dissociation Inhibitor Alpha; RHOGDI; GDIA1; Rho GDP Dissociation Inhibitor (GDI) Alpha; Rho GDP-Dissociation Inhibitor 1; GDP-Dissociation Inhibitor, Aplysia RAS-Related 1; Epididymis Secretory Sperm Binding Protein Li 47e; Rho-GDI Alpha; HEL-S-47e; Rho GDI 1; RHOGDI-1; NPHS8 Background: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Research Area: Signal Transduction