KD-Validated ASPSCR1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated ASPSCR1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:ASPSCR1; ASPSCR1 Tether For SLC2A4, UBX Domain Containing; UBXD9; UBXN9; ASPL; TUG; Tether Containing UBX Domain For GLUT4; ASPS; Alveolar Soft Part Sarcoma Chromosomal Region Candidate Gene 1 Protein; Alveolar Soft Part Sarcoma Chromosome Region, Candidate; ASPSCR1, UBX Domain Containing Tether For SLC2A4; Renal Papillary Cell Carcinoma Protein 17; Alveolar Soft Part Sarcoma Locus; UBX Domain-Containing Protein 9; UBX Domain Protein 9; RCC17; Renal Cell Carcinoma Gene On Chromosome 17; Renal Cell Carcinoma, Papillary, 17; ASPCR1 Background: The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011] Research Area: Signal Transduction