KD-Validated ATIC Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated ATIC Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:ATIC; 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase; PURH; IMPCHASE; AICARFT; Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase; AICAR Transformylase/Inosine Monophosphate Cyclohydrolase; Bifunctional Purine Biosynthesis Protein ATIC; 5-Aminoimidazole-4-Carboxamide-1-Beta-D-Ribonucleotide Transformylase/Inosinicase; AICAR Formyltransferase/IMP Cyclohydrolase Bifunctional Enzyme; Epididymis Secretory Sperm Binding Protein Li 70p; Bifunctional Purine Biosynthesis Protein PURH; AICARFT/IMPCHASE; HEL-S-70p; AICAR Background: This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009] Research Area: Epigenetics and Nuclear Signaling,Signal Transduction,Metabolism