KD-Validated ATP7B Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated ATP7B Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:ATP7B; ATPase Copper Transporting Beta; Copper-Transporting ATPase 2; Copper Pump 2; WND; ATPase, Cu++ Transporting, Beta Polypeptide; Wilson Disease-Associated Protein; PWD; WC1; ATPase, Cu++ Transporting, Beta Polypeptide (Wilson Disease); ATPase, Cu(2+)- Transporting, Beta Polypeptide; Copper-Transporting Protein ATP7B; Wilson Disease; EC 7.2.2.8; EC 3.6.3.4; EC 3.6.3; WD Background: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. [provided by RefSeq, Dec 2019] Research Area: Signal Transduction,Metabolism