

KVAb00382-50ul · 50ul
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Description
EnkiLife offers the KD-Validated BCAM Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:BCAM; Basal Cell Adhesion Molecule (Lutheran Blood Group); F8/G253; CD239; B-CAM; LU; Basal Cell Adhesion Molecule (Lu And Au Blood Groups); B-CAM Cell Surface Glycoprotein; Basal Cell Adhesion Molecule; Auberger B Antigen; F8/G253 Antigen; MSK19; Lutheran Blood Group (Auberger B Antigen Included); Lutheran Blood Group Variant LUGA; Lutheran Blood Group Glycoprotein; B-Cell Adhesion Molecule; Lutheran Antigen; CD239 Antigen; AU Background: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] Research Area: Cardiovascular,Immunology







