KD-Validated Bone Morphogenetic Protein 6 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Bone Morphogenetic Protein 6 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:BMP6; Bone Morphogenetic Protein 6; VGR1; VGR; Vegetal Related Growth Factor (TGFB-Related); VG-1-Related Protein; VG-1-R; BMP-6; VGR-1; IO Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016] Research Area: Signal Transduction,Cell Biology,Stem Cells