KD-Validated BUB1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated BUB1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:BUB1; BUB1 Mitotic Checkpoint Serine/Threonine Kinase; HBUB1; BUB1A; BUB1L; Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1; Budding Uninhibited By Benzimidazoles 1 (Yeast Homolog); Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast); BUB1 Budding Uninhibited By Benzimidazoles 1 Homolog; Budding Uninhibited By Benzimidazoles 1 Homolog; Putative Serine/Threonine-Protein Kinase; Mitotic Spindle Checkpoint Kinase; EC 2.7.11.1; MCPH30 Background: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Research Area: Cell Biology,Cancer