KD-Validated C4BPB Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated C4BPB Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500 Alternative Names of Immunogen:C4BPB; Complement Component 4 Binding Protein Beta; C4b-Binding Protein Beta Chain; C4BP; Complement Component 4 Binding Protein, Beta Chain; Complement Component 4-Binding Protein, Beta; C4b Binding Protein, Beta Chain Background: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008] Research Area: Immunology