KD-Validated Caspase 10 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Caspase 10 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:CASP10; Caspase 10; MCH4; FAS-Associated Death Domain Protein Interleukin-1B-Converting Enzyme 2; FLICE-2; Caspase 10, Apoptosis-Related Cysteine Protease; ICE-Like Apoptotic Protease 4; Caspase-10; CASP-10; FLICE2; Caspase 10, Apoptosis-Related Cysteine Peptidase; Caspase 10 Apoptosis-Related Cysteine Peptidase; Interleukin-1B-Converting Enzyme; Apoptotic Protease MCH-4; Apoptotic Protease Mch-4; FADD-Like ICE2; EC 3.4.22.63; ALPS2 Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011] Research Area: Cell Biology,Cancer,Metabolism