

KVAb00478-100ul ยท 100ul
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Description
EnkiLife offers the KD-Validated Cathepsin D LC Rabbit Polyclonal Antibody. This antibody reacts with Human and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2,500 Alternative Names of Immunogen:CTSD; Cathepsin D; CLN10; CPSD; Ceroid-Lipofuscinosis, Neuronal 10; EC 3.4.23.5; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D (Lysosomal Aspartyl Protease); Lysosomal Aspartyl Peptidase; Lysosomal Aspartyl Protease; HEL-S-130P; EC 3.4.23 Background: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015] Research Area: Neuroscience,Signal Transduction,Cancer,Cell Biology,Neuroscience