KD-Validated CBX2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated CBX2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:CBX2; Chromobox 2; M33; Cell Division Cycle Associated 6; Chromobox Protein Homolog 2; MGC10561; CDCA6; Chromobox Homolog 2 (Pc Class Homolog, Drosophila); Chromobox Homolog 2 (Drosophila Pc Class); Pc Class Homolog (Drosophila); Chromobox Homolog 2; Pc Class Homolog; Modifier 3; SRXY5 Background: This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010] Research Area: Epigenetics and Nuclear Signaling