KD-Validated CD163 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated CD163 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:CD163; CD163 Molecule; M130; SCARI1; MM130; Scavenger Receptor Cysteine-Rich Type 1 Protein M130; Hemoglobin Scavenger Receptor; CD163 Antigen; Macrophage-Associated Antigen Background: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] Research Area: Immunology,Cardiovascular