KD-Validated CD82 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated CD82 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:CD82; CD82 Molecule 2; TSPAN27; IA4; CD82 Antigen; KAI1; R2; Kangai 1 (Suppression Of Tumorigenicity 6, Prostate; CD82 Antigen (R2 Leukocyte Antigen, Antigen Detected By Monoclonal And Antibody IA4)); Metastasis Suppressor Kangai-1; Inducible Membrane Protein R2; Tetraspanin-27; C33 Antigen; Tspan-27; SAR2; Suppressor Of Tumorigenicity 6 Protein; Suppression Of Tumorigenicity 6; R2 Leukocyte Antigen; GR15; 4F9; C33 Background: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Research Area: Immunology,Epigenetics and Nuclear Signaling,Cancer