KD-Validated CDKN2C Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated CDKN2C Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:CDKN2C; Cyclin Dependent Kinase Inhibitor 2C; INK4C; P18; Cyclin-Dependent Kinase Inhibitor 2C (P18, Inhibits CDK4); Cyclin-Dependent Kinase 4 Inhibitor C; P18-INK6; Cyclin-Dependent Kinase 6 Inhibitor P18; Cyclin-Dependent Kinase 6 Inhibitor; Cyclin-Dependent Inhibitor; CDK6 Inhibitor P18; P18-INK4C; P18-INK4c; CDKN6 Background: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008] Research Area: Cell Biology,Epigenetics and Nuclear Signaling,Cancer