KD-Validated Cell Division Cycle 45 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Cell Division Cycle 45 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:CDC45; Cell Division Cycle 45; CDC45L2; CDC45L; Cell Division Control Protein 45 Homolog; Human CDC45; PORC-PI-1; CDC45 (Cell Division Cycle 45, S.Cerevisiae, Homolog)-Like; CDC45 Cell Division Cycle 45-Like (S. Cerevisiae); Cell Division Cycle 45 Homolog (S. Cerevisiae); CDC45 Cell Division Cycle 45 Homolog; CDC45 Cell Division Cycle 45-Like; Cell Division Cycle 45 Homolog; Cell Division Cycle 45-Like 2; CDC45-Related Protein; MGORS7 Background: The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Research Area: Epigenetics and Nuclear Signaling,Cell Biology