KD-Validated Chromodomain Helicase DNA Binding Protein 3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Chromodomain Helicase DNA Binding Protein 3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:CHD3; Chromodomain Helicase DNA Binding Protein 3; ZFH; Chromodomain-Helicase-DNA-Binding Protein 3; Mi-2 Autoantigen 240 KDa Protein; ATP-Dependent Helicase CHD3; Zinc Finger Helicase; Mi2-ALPHA; Mi-2a; CHD-3; HZFH; Zinc-Finger Helicase (Snf2-Like); EC 3.6.4.12; MI2-ALPHA; Mi2-Alpha; EC 3.6.1; SNIBCPS; MI-2A Background: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Research Area: Immunology,Epigenetics and Nuclear Signaling