KD-Validated Contactin Associated Protein 1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Contactin Associated Protein 1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,M and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:CNTNAP1; Contactin Associated Protein 1; P190; CNTNAP; CASPR; NRXN4; Contactin-Associated Protein 1; Neurexin IV; Neurexin-4; Caspr1; Caspr; Neurexin 4; CHN3 Background: The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009] Research Area: Neuroscience