KD-Validated COX6C Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated COX6C Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:400-1:2,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:COX6C; Cytochrome C Oxidase Subunit 6C; Cytochrome C Oxidase Polypeptide VIc; Cytochrome C Oxidase Subunit VIc Preprotein; Epididymis Secretory Sperm Binding Protein; Cytochrome C Oxidase Subunit VIc Background: Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010] Research Area: Tags & Cell Markers,Signal Transduction,Cancer,Metabolism