KD-Validated CRADD Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated CRADD Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:CRADD; CASP2 And RIPK1 Domain Containing Adaptor With Death Domain; RAIDD; RIP-Associated ICH1/CED3-Homologous Protein With Death Domain; Death Domain-Containing Protein CRADD; RIP-Associated Protein With A Death Domain; Caspase And RIP Adaptor With Death Domain; Caspase And RIP Adapter With Death Domain; Death Domain Containing Protein CRADD; Death Adaptor Molecule RAIDD; CRADD/LYZ Fusion; MRT34 Background: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Research Area: Cell Biology,Cancer