KD-Validated CRTC3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated CRTC3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:CRTC3; CREB Regulated Transcription Coactivator 3; CREB-Regulated Transcription Coactivator 3; FLJ21868; TORC-3; TORC3; Transducer Of Regulated CAMP Response Element-Binding Protein (CREB) 3; Transducer Of Regulated CAMP Response Element-Binding Protein 3; Transducer Of Regulated CREB Protein 3; Transducer Of CREB Protein 3 Background: This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012] Research Area: Microbiology,Epigenetics and Nuclear Signaling