KD-Validated CYP1A2 Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated CYP1A2 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:CYP1A2; Cytochrome P450 Family 1 Subfamily A Member 2; P3-450; CP12; Cytochrome P450, Subfamily I (Aromatic Compound-Inducible), Polypeptide 2; Cytochrome P450, Family 1, Subfamily A, Polypeptide 2; Hydroperoxy Icosatetraenoate Dehydratase; Cholesterol 25-Hydroxylase; Cytochrome P450 1A2; Cytochrome P(3)450; Cytochrome P450-P3; Cytochrome P450 4; EC 1.14.14.1; CYPIA2; Flavoprotein-Linked Monooxygenase; Aryl Hydrocarbon Hydroxylase; Microsomal Monooxygenase; Xenobiotic Monooxygenase; Dioxin-Inducible P3-450; EC 4.2.1.152; P450 Form 4; P450(PA) Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008] Research Area: Biochemicals