KD-Validated CYP7B1 Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated CYP7B1 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:200-1:1,000; FC 1:100-1:1,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:CYP7B1; Cytochrome P450 Family 7 Subfamily B Member 1; Cytochrome P450, Subfamily VIIB (Oxysterol 7 Alpha-Hydroxylase), Polypeptide 1; 25/26-Hydroxycholesterol 7-Alpha-Hydroxylase; 24-Hydroxycholesterol 7-Alpha-Hydroxylase; 3-Hydroxysteroid 7-Alpha Hydroxylase; Oxysterol 7-Alpha-Hydroxylase; Cytochrome P450 7B1; SPG5A; Cytochrome P450, Family 7, Subfamily B, Polypeptide 1; Spastic Paraplegia 5A (Autosomal Recessive); 25-Hydroxycholesterol 7-Alpha-Hydroxylase; EC 1.14.14.26; EC 1.14.14.29; CBAS3; CP7B Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016] Research Area: Cardiovascular,Signal Transduction,Cancer,Metabolism,Cardiovascular