KD-Validated Cystathionine Beta-Synthase Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Cystathionine Beta-Synthase Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:CBS; Cystathionine Beta-Synthase; HIP4; Serine Sulfhydrase; Beta-Thionase; EC 4.2.1.22; Cystathionine Beta-Synthase-Like Protein; Cystathionine-Beta-Synthase; Methylcysteine Synthase; CBSL Background: The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016] Research Area: Signal Transduction,Cancer,Metabolism