KD-Validated Cytochrome B5 Reductase 3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Cytochrome B5 Reductase 3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:CYB5R3; Cytochrome B5 Reductase 3; B5R; NADH-Cytochrome B5 Reductase 3; DIA1; Diaphorase-1; EC 1.6.2.2; NADH-Cytochrome B5 Reductase 3 Membrane-Bound Form; Diaphorase (NADH) (Cytochrome B-5 Reductase; NADH-Cytochrome B5 Reductase 3 Soluble Form; Mutant NADH-Cytochrome B5 Reductase; Cytochrome B5 Reductase Background: This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010] Research Area: Cardiovascular,Signal Transduction,Metabolism