KD-Validated DGCR8 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated DGCR8 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:DGCR8; DGCR8 Microprocessor Complex Subunit; DGCRK6; DiGeorge Syndrome Critical Region Gene 8; Microprocessor Complex Subunit DGCR8; DiGeorge Syndrome Critical Region 8; C22orf12; Pasha; Gy1; DGCR8, Microprocessor Complex Subunit; Chromosome 22 Open Reading Frame 12; C22ORF12; PASHA; GY1 Background: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010] Research Area: Epigenetics and Nuclear Signaling