KD-Validated Dihydropyrimidine Dehydrogenase Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Dihydropyrimidine Dehydrogenase Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:DPYD; Dihydropyrimidine Dehydrogenase; DPD; Dihydrothymine Dehydrogenase; Dihydrouracil Dehydrogenase ; Dihydropyrimidine Dehydrogenase [NADP(+)]; EC 1.3.1.2; DHPDHase; DHPDHASE; DYPD; DHP Background: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] Research Area: Signal Transduction,Metabolism