KD-Validated DMAP1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated DMAP1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:DMAP1; DNA Methyltransferase 1 Associated Protein 1; DNMAP1; KIAA1425; DNMTAP1; MEAF2; EAF2; SWC4; DNA Methyltransferase 1-Associated Protein 1; FLJ11543; DNMT1 Associated Protein 1; DNMT1-Associated Protein 1 Background: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling