KD-Validated DNA Damage Inducible Transcript 3 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated DNA Damage Inducible Transcript 3 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:DDIT3; DNA Damage Inducible Transcript 3; GADD153; CHOP10; CHOP; C/EBP Zeta; Growth Arrest And DNA Damage-Inducible Protein GADD153; CCAAT/Enhancer-Binding Protein Homologous Protein; DNA Damage-Inducible Transcript 3 Protein; C/EBP-Homologous Protein 10; Alternative DDIT3 Protein; AltDDIT3; CHOP-10; Growth Arrest And DNA-Damage-Inducible Gene; DDIT3 Upstream Open Reading Frame Protein; DNA-Damage-Inducible Transcript 3; C/EBP Homologous Protein; C/EBP-Homologous Protein; C/EBPzeta; DDIT-3; CEBPZ Background: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010] Research Area: Epigenetics and Nuclear Signaling,Stem Cells,Developmental Biolopy,Metabolism