KD-Validated DNA Polymerase Gamma Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated DNA Polymerase Gamma Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:DNA Polymerase Gamma, Catalytic Subunit; POLG1; POLGA; Mitochondrial DNA Polymerase Catalytic Subunit; Polymerase (DNA) Gamma, Catalytic Subunit; Polymerase (DNA Directed), Gamma; DNA Polymerase Subunit Gamma-1; PolG-Alpha; EC 2.7.7.7; MDP1; Mitochondrial Polymerase Gamma Catalytic Subunit; MTDPS4A; MTDPS4B; MIRAS; SANDO; SCAE; PEO Background: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling,Metabolism