KD-Validated DTNA Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated DTNA Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:100-1:1,000 Alternative Names of Immunogen:DTNA; Dystrobrevin Alpha; DRP3; Dystrophin-Related Protein 3; D18S892E; DTN; DTN-1; DTN-2; DTN-3; DTN-A; Dystrobrevin, Alpha; Alpha-Dystrobrevin; LVNC1 Background: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Research Area: Neuroscience,Signal Transduction