KD-Validated DYNLL1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated DYNLL1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:DYNLL1; Dynein Light Chain LC8-Type 1; DLC1; DLC8; PIN; DNCL1; LC8; Protein Inhibitor Of Neuronal Nitric Oxide Synthase; Dynein, Cytoplasmic, Light Polypeptide 1; Dynein Light Chain 1, Cytoplasmic; 8 KDa Dynein Light Chain; DNCLC1; Hdlc1; HDLC1; Cytoplasmic Dynein Light Polypeptide; LC8a Background: Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] Research Area: Cell Biology,Neuroscience,Signal Transduction,Epigenetics and Nuclear Signaling,Cancer,Metabolism