KD-Validated Dysferlin Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Dysferlin Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,M and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:DYSF; Dysferlin; FER1L1; Limb Girdle Muscular Dystrophy 2B (Autosomal Recessive); Fer-1-Like Family Member 1; Fer-1-Like Protein 1; LGMD2B; Dystrophy-Associated Fer-1-Like Protein; Dystrophy-Associated Fer-1-Like 1; LGMDR2; MMD1 Background: The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008] Research Area: Cell Biology,Neuroscience