KD-Validated Dyskerin Pseudouridine Synthase 1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Dyskerin Pseudouridine Synthase 1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:DKC1; Dyskerin Pseudouridine Synthase 1; NOLA4; XAP101; NAP57; H/ACA Ribonucleoprotein Complex Subunit DKC1; H/ACA Ribonucleoprotein Complex Subunit; Nopp140-Associated Protein Of 57 KDa; Nucleolar Protein Family A Member 4; Dyskeratosis Congenita 1, Dyskerin; Nucleolar Protein NAP57; SnoRNP Protein DKC1; CBF5 Homolog; Dyskerin; CBF5; DKC; EC 5.4.99.-; EC 5.4.99; DYSKERIN; CHINE1; Cbf5; DKCX Background: This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Research Area: Epigenetics and Nuclear Signaling