KD-Validated ECT2 Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated ECT2 Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:100-1:1,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:ECT2; Epithelial Cell Transforming 2; ARHGEF31; Epithelial Cell-Transforming Sequence 2 Oncogene; Protein ECT2; Epithelial Cell Transforming Sequence 2 Oncogene Background: The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017] Research Area: Cell Biology