KD-Validated EIF2AK2 Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated EIF2AK2 Mouse Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:EIF2AK2; Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2; PKR; Protein Kinase R; PPP1R83; PRKR; Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent; Interferon-Induced, Double-Stranded RNA-Activated Protein Kinase; Protein Phosphatase 1, Regulatory Subunit 83; Tyrosine-Protein Kinase EIF2AK2; Protein Kinase RNA-Activated; Protein Kinase RNA-Regulated; P1/EIF-2A Protein Kinase; EIF-2A Protein Kinase 2; P68 Kinase; Eukaryotic Translation Initiation Factor 2-Alpha Kinase 2; Interferon-Inducible RNA-Dependent Protein Kinase; Double Stranded RNA Activated Protein Kinase; Interferon-Inducible ElF2alpha Kinase; EC 2.7.11.1; EC 2.7.10.2; EIF2AK1; LEUDEN; DYT33 Background: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021] Research Area: Signal Transduction