KD-Validated EIF2AK4 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated EIF2AK4 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:EIF2AK4; Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4; GCN2; KIAA1338; EIF-2-Alpha Kinase GCN2; GCN2-Like Protein; Eukaryotic Translation Initiation Factor 2-Alpha Kinase 4; General Control Nonderepressible; GCN2 EIF2alpha Kinase; EIF-2-Alpha Kinase; EC 2.7.11.1; PVOD2 Background: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014] Research Area: Epigenetics and Nuclear Signaling,Signal Transduction