KD-Validated Endothelin Receptor Type B Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated Endothelin Receptor Type B Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:EDNRB; Endothelin Receptor Type B; ETB; Endothelin Receptor Non-Selective Type; ET-BR; HSCR2; ET-B; ETRB; HSCR; Endothelin Receptor Subtype B1; Hirschsprung Disease 2; ABCDS; ETB1; ETBR; WS4A Background: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016] Research Area: Signal Transduction