KD-Validated EOGT Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KD-Validated EOGT Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:EOGT; EGF Domain Specific O-Linked N-Acetylglucosamine Transferase; AER61; EGF Domain-Specific O-Linked N-Acetylglucosamine (GlcNAc) Transferase; EGF Domain-Specific O-Linked N-Acetylglucosamine Transferase; Extracellular O-Linked N-Acetylglucosamine Transferase; AER61 Glycosyltransferase; FLJ33770; C3orf64; EOGT1; Chromosome 3 Open Reading Frame 64; EGF-O-GlcNAc Transferase; EC 2.4.1.255; C3ORF64; AOS4 Background: This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins. This enzyme modifies proteins containing eukaryotic growth factor (EGF)-like domains, including the Notch receptor, thereby regulating developmental signalling. Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] Research Area: Cell Biology