KD-Validated ETFA Mouse Monoclonal Antibody

Description

EnkiLife offers the KD-Validated ETFA Mouse Monoclonal Antibody. This antibody reacts with Human,M and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:ETFA; Electron Transfer Flavoprotein Subunit Alpha; MADD; GA2; EMA; Electron Transfer Flavoprotein Subunit Alpha, Mitochondrial; Multiple Acyl-CoA Dehydrogenase Deficiency; Glutaric Aciduria II; Alpha-ETF; Electron-Transfer-Flavoprotein, Alpha Polypeptide; Electron Transfer Flavoprotein, Alpha Polypeptide; Electron Transfer Flavoprotein Alpha Subunit; Epididymis Secretory Sperm Binding Protein Background: ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Research Area: Signal Transduction,Cancer,Metabolism